Engagement Models

Whether you run trials in-house, use multiple vendors, or fully outsource to a CRO, Prana can help. We adapt to your operating model—not the other way around.

Engagement options: Pod-based (4-12 weeks) • Workstream-based • Cohort-based • Full study delivery

Sponsor-Led Operations (In-House)

Best for: Teams that want to stay in control but need fast execution capacity.

How Prana Helps: Targeted "pods" to hit milestones when internal teams are bandwidth-constrained.

Example support:

  • Study Start-up Activation Pod: End-to-end site activation support (essential docs, trackers, follow-ups, activation governance) to accelerate "greenlit to enroll" readiness
  • Surge support for peak workload periods (country/site packages, vendor coordination, status reporting)

Hybrid Operating Model (Sponsor + Partners)

Best for: Sponsors using multiple vendors who want one team to close operational gaps and reduce variance.

How Prana Helps: Bridge gaps with discrete workstreams or end-to-end ownership for defined scope.

Example support:

  • Cohort/work-package ownership (e.g., early-phase oncology cohorts or priority sub-studies)
  • eTMF + inspection readiness: Weekly QC cadence, TMF health, reconciliation, readiness checks
  • RBQM + monitoring support: Centralized monitoring, signal/action tracking, hybrid monitoring cadence

Fully Outsourced Research Management

Best for: Sponsors who need a focused partner to recover milestones, or sponsors seeking comprehensive research management.

How Prana Helps: Targeted support without disrupting existing relationships, or full study delivery as primary partner.

Example support:

  • Recovery support for underperforming workstreams (startup delays, site engagement, enrollment recovery, TMF remediation, RBQM signal follow-through)
  • Independent oversight + rapid corrective action plans to protect timelines and quality
  • Full study delivery from protocol to closeout as primary research partner

What You Get With Every Engagement

Senior-Led Delivery

Executive operators stay attached to your program. You get direct access to decision-makers, not layers of coordinators.

Glass-Box Transparency

Real-time dashboards show activation blockers, RBQM action logs, TMF health, and budget variance. You see what we see.

24-48h Execution Cadence

Your study moves daily, not weekly. Our global ops pod turns documents, QC, and reporting in 24-48 hours.

Written Delivery Targets

We commit to specific milestones with governance to those targets. Outcomes over hours—you pay for results.

Partnership Opportunities

We also partner with research organizations who need targeted support for specific workstreams or geographies. If you're looking for a reliable partner to help deliver on high-priority programs, let's talk.

Our flexible model means we can plug into your delivery structure without disrupting your client relationships or operating model.

Let's find the right model for you.

Tell us about your program and we'll propose an engagement that fits your needs and operating model.

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